Opioid conversion calculator morphine equivalents advanced. Calculate total dose oral morphine over 24 hours, 2 x 90 mg 180 mg. Duragesic fentanyl transdermal system is a skin patch that belongs to a group of medicines called narcotic analgesics or opioid analgesics. Didnt know where else to put this, but i was recently switched from morphine 60mg er to the fentanyl duragesic patch. For mild pain, the starting regimen should be a nonsteroidal antiinflammatory drug nsaid or acetaminophen. This calculator should not be used to determine doses when converting a patient from one opioid to another. Most of the above oral opioids are available as generics. Equianalgesic dose ratios are only approximations and do not account for genetic factors, incomplete crosstolerance, and pharmacokinetics. Made by orthomcneil, duragesic patches are nearly 100 more potent than morphine and can provide up to 72 hours 3 days of pain relieve when used as directed. Is there a conversion for going from fentora to duragesic patch i am currently on 50mcg duragesic patch every 3days and 400mcg fentora. Fentanyl patches durogesic for chronic pain nps medicinewise. Duragesic patches are intended for transdermal use on intact skin only. Conversion from morphine or equivalent to fentanyl transdermal calculate the total 24hour morphine dose or morphineequivalent. Demystifying opioid conversion calculations 83 chapter 5 transdermal and parenteral fentanyl dosage calculations and conversions objectives after reading this chapter and completing all practice problems, the participant will be able to.
I thought the weird flu like symptoms might be a result of the new drug, but apparently it has to be withdrawal from the morphine. Option for converting final output into an equivalent fentanyl patch strength as long as published guidelines exist for the current dose. Fentanyl is also available as a sustained release transdermal patch which when. Because extendedrelease products such as butrans deliver the opioid over an extended period of time, there is a greater risk for overdose and death, due to the larger amount of buprenorphine present. Methadone and fentanyl are generally safe and considered good options in patients with renal insufficiency. Do not apply the new patch to the same place as the last one. The total daily morphine milligram equivalents mme will be displayed. Transdermal and parenteral fentanyl dosage calculations and. Instead of increasing the dosage of the patch, he gave me ultracet to handle the breakthrough pain. Several companies manufacture a generic duragesic fentanyl patch product, including actavis u. Each 2 mg po morphine approximately equivalent to 1 mcghr fentanyl patch e.
Select microgram per hour dose of transdermal fentanyl based. For moderate pain, an opioid agonist eg, hydrocodone. Fentanyl is also available as a sustained release transdermal patch which when applied to a fleshy nonbony region of the body functions as a basal pain medication for 72 hours. Convert the iv dose to the equianalgesic oral morphine dose using a ratio. The table is based on oral dosing for chronic noncancer pain. Enter 24hour total doses below, then click the convert button to display 24hour equianalgesic doses. Fentanyl accumulates to form a depot in the skin below the. It has a rapid onset and its effects generally last less than two hours. Transdermal and parenteral fentanyl dosage calculations.
What are the steps for converting from morphine or. Oct 15, 2019 the conversion doses in these tables are only for the conversion from one of the listed oral or parenteral opioid analgesics to duragesic. Smith is now unable to swallow and so the morphine needs to be converted into a transdermal fentanyl patch. Converting to transdermal fentanyl palliative care network. Duragesic is used to treat moderate to severe chronic, constant pain. Duragesics skin patch form is used to treat aroundtheclock pain chronic pain that is moderate to severe and expected to last for weeks or longer. Do not change fentanyl patches to another opioid in a dying patient, continue the fentanyl patch and use an additional opioid as required via csci. Describe the pharmacokinetics of transdermal fentanyl, and variables that can influence dosing. Find out what health conditions may be a health risk when taken with duragesic transdermal. Fentanyl, also spelled fentanil, is an opioid used as a pain medication and together with other medications for anesthesia. Converting from oral morphine to fentanyl transdermal patch. Medically, fentanyl is used by injection, as a patch on the skin, as a nasal spray, or in the mouth. For each opioid, select the strength from the drop down menu and enter the number of tablets per day for fentanyl transdermal, see instructions below.
In other words, the conversion factor not accounting for days of use would be 6025 or 2. The united states food and drug administration has determined that the generic versions of duragesic are equivalent to the brandname drug. Fentanyl duragesic is a moderately priced drug used to treat chronic pain. Methadone conversion algorithm including the ability to edit equianalgesic conversion factors if necessary in order to reflect any changes in the literature. Patches conversion doses drug name drug dose equivalent oral morphine dose fentanyl 25 patch 25microgramshour 30mg to 4mg24hours fentanyl 50 patch 50 microgramshour 5mg to 224mg24hours fentanyl 75 patch 75 microgramshour 225mg to 314mg24hours fentanyl 100 patch 100 microgramshour 315mg to 404mg24hours transtec 52. Duragesic patch fentanyl patch rationale for inclusion in pa. An alternative algorithm for dosing transdermal fentanyl for. Oral morphine milligram equivalent conversion table updated 8. Stronger dosed duragesic patches may be available for particularly severe cases of chronic pain. Fentanyl transdermal patch is a prescription medication thats used to treat chronic pain in opioidtolerant people.
The transdermal patch is a longacting formulation with a delayed onset of effect initially and a prolonged duration of action. I will run out of fentora 2 days early and am wondering if i could stick on an extra patch to avoid withdrawals. It is not intended to be and should not be interpreted as medical advice or a diagnosis of any health or fitness problem, condition or disease. This calculator is intended for calculating the morphine equivalent dose med dose for a patient taking one or more opioid medications. Treatment with oxycontin can be initiated after the transdermal fentanyl patch has been removed for at least 18 hours. The content on this site is presented in a summary fashion, and is intended to be used for educational and entertainment purposes only. Duragesic fda prescribing information, side effects and uses. Duragesic is a brand name for the narcotic pain medicine fentanyl. Butrans contains buprenorphine, a schedule iii controlled substance.
My doctor refuses to increase my dosage of the patch even though i dont feel it is effective as it was. Aug 18, 2012 the duragesic fentanyl patch is used to treat chronic pain by supplying a steady dose of fentanyl a powerful opioid pain medication over an extended period of timeusually up to 72 hours. Morphine milligram equivalent mme calculator instructions. Opioid opiate equianalgesia conversion calculator 12 mar 2017 online calculator to convert equianalgesic doses of opioid narcotic because transdermal fentanyl has a delayed onset and onset of peak oral opioid dosing equivalents and conversions university ofhydrocodone vicodin, norco, lorcet morphine to methadone conversion each 2 mg po morphine approximately equivalent to 1. Converting to transdermal fentanyl palliative care. Morphine milligram equivalents mme calculator mdcalc. Quickwhat dose of the transdermal fentanyl patch duragesica is equianalgesic to a 3 mghr morphine continuous infusion. Remember to enter all opioids the patient is taking. Duragesic s skin patch form is used to treat aroundtheclock pain chronic pain that is moderate to severe and expected to last for weeks or longer. The conversion doses in these tables are only for the conversion from one of the listed oral or parenteral opioid analgesics to duragesic.
Converting to transdermal fentanyl palliative care network of. However, since the fentanyl patch remains in place for 3 days, we have multiplied the conversion factor by 3 2. Conversion oraliv opioids to fentanyl transdermal each transdermal system is worn continuously for up to 72 hr see administration tables found in prescribing information cannot be used to convert from fentanyl transdermal to another opioid because conversions will result in an overestimation of the dose of new opioid and may result in fatal. The duragesic patch is an adhesive patch containing narcotic pain medicine typically narcotic analgesics or opioid analgesics. Fentanyl transdermal patch duragesic is a prescription medication used to treat severe chronic pain such as cancer. Butrans exposes users to the risks of opioid addiction, abuse, and misuse. Dose conversion tool butrans buprenorphine transdermal. Caution should be used in older adults or patients with cachexiafentanyl is lipid soluble and requires subcutaneous fat for proper absorption. In the iv form fentanyl is often used in icus for pain control due to its rapid onset of action and due to the minimal histamine release associated with fentanyl in comparison to morphine.
Durogesic 100 mcg 100mcg1patch 1 patch fentanyl citrate drug information. Fentanyl patch dosing determination based on current opioid therapy. The tables cannot be used to convert from duragesic to another opioid because these conversions will result in an overestimation of the dose of the new opioid these conversions are conservative and may. Fentanyl patch converter globalrph conversion from other opiates. The duragesic fentanyl patch is used to treat chronic pain by supplying a steady dose of fentanyl a powerful opioid pain medication over an extended period of timeusually up to 72 hours. Round up or down based on patient factors and available patch sizes. Current breakthrough opioid entered to be what the patient is actually taking rather than what has been prescribed. Jan 29, 2018 methadone and fentanyl are generally safe and considered good options in patients with renal insufficiency. I will run out of fentora 2 days early and am wondering if i could stick on an extra patch to avoid withdrawals i am prescribed the fentora. Duragesic label page 1 full prescribing information for use. Fentanyl patch converter globalrph conversion from other.
So, you use that and add 15mg for your breakthrough dose and there you have it. The duragesic cii patch is manufactured by alza corporation and distributed by janssen pharmaceutica products, l. The conversion ratio of certain opioids can be dependent on the dose of the original opioid. This is especially important for fentanyl and methadone conversions. Some experts use this conversion in cancer patients.
The duragesic transdermal system patch is used for the management of persistent, moderate to severe chronic pain in opioidtolerant patients when a continuous, aroundtheclock opioid analgesic is needed for an extended period of time. Duragesic fentanyl transdermal system cii pain patch. In the case of converting morphine to methadone, methadone has a relative potency of 4. The 50, 75, and 100 mcghr patches should only be used in patients already on and tolerant to opioid therapy. Duragesic fentanyl transdermal drugs requiring prior authorization drugs requiring prior authorization label name gcn duragesic 12 mcghr patch 24635 duragesic 25 mcghr patch 19200 duragesic 50 mcghr patch 19201 duragesic 75 mcghr patch 19202 duragesic 100 mcghr patch 19203 fentanyl 12 mcghr patch 24635.
Webmd provides common contraindications for duragesic transdermal. This table should not be used to convert from duragesic to other. Fentanyl is also used as a recreational drug, often mixed with heroin or cocaine. Opioid conversion calculator for morphine equivalents.
Online calculator to convert equianalgesic doses of opioid narcotic analgesics. Duragesic patches typically come in the following doses. Scottish palliative care guidelines fentanyl patches. Opioid oral morphine milligram equivalent mme conversion. Repeat steps 2 through 6above when applying a new duragesic patch. The fentanyl in the patch diffuses through the skin and depots in the adipose tissue and provides sustained pain relief. Canadian guideline for safe and effective use of opioids for. Using damaged or cut duragesic patches can lead to the rapid release of the contents of the duragesic patch and absorption of a potentially fatal dose of fentanyl. Side effects may include profuse sweating, coughing, nausea, diarrhea, and tearing. Canadian guideline for safe and effective use of opioids. Apply 75 microgram fentanyl patch concurrently with the last dose of long acting oral morphine 90mg. Remove a duragesic patch after wearing it for 3 days 72 hours. Fentanyl patch conversions package insert recommendations.
Duragesic patch dose duragesic patches are fentanyl transdermal systems that deliver extremely potent pain medication to patients via patches placed on the skin. Morphine milligram equivalent mme calculator nyc health. Conversions to and from fentanyl transdermal are notoriously tricky, requiring knowledge of the published conversion data, general opioid pharmacology, and a generous dose of common sense. People who are on the 25ughr patch feel they are on the lowest dose, so they can just drop off right from there. Withdrawal symptoms, drug interactions, dosage, and pregnancy and breastfeeding safety are provided. Duragesic label page 1 full prescribing information for. Duragesic is a longacting extendedrelease opioid pain medicine narcotic that can put you at risk for overdose and death. Equianalgesic dosing of opioids for pain management. Although there has been no systematic assessment of such conversion, start with a conservative conversion. This calculator, which is based roughly on information provided by janssen pharmaceuticals inc. I have been on the duragesic patch for about a year and a half now. Even if you take your dose correctly as prescribed you are at risk for opioid addiction, abuse, and misuse that can lead to overdose or death. Duragesic fentanyl transdermal dosing, indications. Generic fentanyl is covered by some medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.
Stop long acting oral morphine after applying patch. John smith, a terminally ill lung cancer patient has pain that is well controlled on morphine sustained action, 90mg every 12 hours. In clinical trials, these ranges of daily oral morphine doses were used as a basis for conversion to duragesic. It should not be used to determine doses when converting a patient from one opioid to another. Serious or lifethreatening breathing problems that can lead to death can. The web page will automatically calculate the total morphine equivalents per day. Choose a different skin site to apply a new duragesic patch. The larger the dose of fentanyl delivered, the larger the patch as of the skins surface area has to be covered to ensure that. Use caution when prescribing opioids at any dosage, and prescribe the lowest effective dose.
So by applying the patch with the last dose of the oral morphine the chances of increasing pain during the drug transition can be avoided. Calculates total daily morphine milligram equivalents. Dispose of the unused part of the patch safely as described in the fentanyl patch care section. See the section below disposing ofa duragesic patch. Fentanyl patch converter globalrph conversion from. There is no completely safe opioid dose, and this calculator does not substitute for clinical judgment. Read the medication guide and, if available, the instructions for use provided by your pharmacist before you start using. Instructions for use duragesic instructions for applying a. Eligible patients using commercial or private insurance can save on outofpocket costs for duragesic. Strength per unit x number of units days supply x mme conversion factor daily med example.
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